Authors: McGaughey, SA; De Rosa, A; Iqbal, S; Beck, FJ; Gurieff, NB; Byrt, CS

Open access courtesy of:

DOI https://doi.org/10.36487/ACG_repo/2515_104

Cite As:
McGaughey, SA, De Rosa, A, Iqbal, S, Beck, FJ, Gurieff, NB & Byrt, CS 2025, 'Bioderived element resource separation technology for waste processing', in S Knutsson, AB Fourie & M Tibbett (eds), Mine Closure 2025: Proceedings of the 18th International Conference on Mine Closure, Australian Centre for Geomechanics, Perth, pp. 1-16, https://doi.org/10.36487/ACG_repo/2515_104

Download citation as:   ris   bibtex   endnote   text   Zotero


Abstract:
New methods for selective recovery of around USD 3.4 trillion worth of critical resources left in mining-influenced water are needed to enable improved waste valorisation and better environmental outcomes. Biological solutions for metal and mineral extraction have evolved over millions of years as they are essential resources for living organisms. These are many of the same critical resources that are required for manufacturing the technologies of the future. Membrane separation mechanisms used by living organisms to manage metal and mineral nutrient uptake and distribution are therefore being leveraged to develop next-generation mining biotechnologies that enable the recovery of critical materials from wastes. Research into mechanisms that diverse plant species use for selective resource separation has led to the development of the bioderived element resource separation technology (BERST) system. BERST is a modular biomimetic membrane system designed to extract permeates of high-purity metals, minerals and clean water from complex mining-influenced feed solutions. The BERST membrane system incorporates collections of bioengineered, highly selective, pore-forming structures inspired by nature and optimised for stability and performance that enable targeted and selective separation of valuable metals and minerals from wastes. Demonstration of selective metal recovery using BERST is at the laboratory-scale prototype testing stage. Deployment of systems like BERST that enable mininginfluenced waters to be separated into high-purity metal, mineral and clean water resources align with the concept of ‘economic rehabilitation’, where the residual value in mining-influenced water is harnessed to improve the social and environmental outcomes of mine closure and operations. BERST is expected to contribute to enabling sustainable management of mininginfluenced waters, reducing environmental impacts and supporting circular practices in the mining industry.

Keywords: membrane, separation, bioengineering, mining-influenced water, valorisation, remediation

References:
Abid, MB, Wahab, RA, Salam, MA, Moujdin, IA & Gzara, L 2023, ‘Desalination technologies, membrane distillation, and electrospinning, an overview’, Heliyon, vol. 9, no. 2,
Almohasin, JA, Balag, J, Miral, VG, Moreno, RV, Tongco, LJ & Lopez, ECR 2023, ‘Green Solvents for Liquid–Liquid Extraction: Recent Advances and Future Trends’, Engineering Proceedings, vol. 56, no. 1,
Aquaporin 2023, Aquaporin Inside CLEAR Classic, fact sheet, viewed 10 April 2025,  
Arsic, M, Byrt, C, De Rosa, A, Hilder, P, Iqbal, S, McGaughey, S, ... Xie, Z 2024, ‘Biomimetic membrane technology developments relevant to sustainable reuse of resources’, Water e-Journal, vol. 10, no. 3,
Bar-On, YM, Phillips, R & Milo, R 2018, ‘The biomass distribution on Earth’, Proceedings of the National Academy of Sciences, vol. 115, no. 25, pp. 6506–6511,
Barone, GD, Emmerstorfer-Augustin, A, Biundo, A, Pisano, I, Coccetti, P, Mapelli, V & Camattari, A 2023, ‘Industrial production of proteins with Pichia pastoris- Komagataella phaffii’, Biomolecules, vol. 13, no. 3,
Bolto, B, Zhang, J, Wu, X & Xie, Z 2020, ‘A review on current development of membranes for oil removal from wastewaters’, Membranes, vol. 10, no. 4,
Byrt, CS, Zhang, RY, Magrath, I, Chan, KX, De Rosa, A & McGaughey, S 2023, ‘Exploring aquaporin functions during changes in leaf water potential’, Frontiers in Plant Science, vol. 14,
CSIRO 2022, Proteins of the future: using precision fermentation to develop new ingredients, viewed 10 April 2025,
CSIRO 2023, Enabling Mine Closure and Transitions: Opportunities for Australian Industry, prepared for CRC TiME.
Daraz, U, Li, Y, Ahmad, I, Iqbal, R & Ditta, A 2023, ‘Remediation technologies for acid mine drainage: recent trends and future perspectives’, Chemosphere, vol. 311,
De Rosa, A, McGaughey, S, Magrath, I & Byrt, C 2023, ‘Molecular membrane separation: plants inspire new technologies’, New Phytologist, vol. 238, no. 1, pp. 33–54,
Deamer, D 2016, ‘Membranes and the origin of life: a century of conjecture’, Journal of Molecular Evolution, vol. 83, pp. 159–168,
Demain, AL & Vaishnav, P 2009, ‘Production of recombinant proteins by microbes and higher organisms’, Biotechnology Advances, vol. 27, no. 3, pp. 297–306,
Dorey, A & Howorka, S 2024, ‘Nanopore DNA sequencing technologies and their applications towards single-molecule proteomics’, Nature Chemistry, vol. 16, pp. 314–334,
Drew, D & Boudker, O 2016, ‘Shared Molecular Mechanisms of Membrane Transporters’, Annual Review of Biochemistry, vol. 85, pp. 543–572,
Epsztein, R, DuChanois, RM, Ritt, CL, Noy, A & Elimelech, M 2020, ‘Towards single-species selectivity of membranes with subnanometre pores’, Nature Nanotechnology, vol. 15, pp. 426–436,
Fan, F, Ren, Y, Zhang, S, Tang, Z, Wang, J, Han, X, ... Tang, B 2024, ‘A bioinspired membrane with ultrahigh Li+/Na+ and Li+/K+ separations enables direct lithium extraction from brine’, Advanced Science, vol. 11, no. 35,
Fang, Y, Jiang, J, Hou, X, Guo, J, Li, X, Zhao, D & Xie, X 2022, ‘Plant protein-coding gene families: Their origin and evolution’, Frontiers in Plant Science, vol. 13,
Flagel, LE & Wendel, JF 2009, ‘Gene duplication and evolutionary novelty in plants’, New Phytologist, vol. 183, no. 3, pp. 557–564,
Fuwad, A, Ryu, H, Han, ED, Lee, JH, Malmstadt, N, Kim, YR, ... Jeon, TJ 2024, ‘Highly permeable and shelf-stable aquaporin biomimetic membrane based on an anodic aluminum oxide substrate’, npj Clean Water, vol. 7,
Habel, J, Hansen, M, Kynde, S, Larsen, N, Midtgaard, SR, Jensen, GV, ... Hélix-Nielsen, C 2015, ‘Aquaporin-Based Biomimetic Polymeric Membranes: Approaches and Challenges’, Membranes, vol. 5, no. 3, pp. 307–351,
Harrington, SA, Connorton, JM, Nyangoma, NIM, McNelly, R, Morgan, YML, Aslam, MF, ... Balk, J 2022, ‘A two-gene strategy increases iron and zinc concentrations in wheat flour, improving mineral bioaccessibility’, Plant Physiology, vol. 191, no. 1,
pp. 528–541,
He, B, Liu, W, Li, J, Xiong, S, Jia, J, Lin, Q, ... Cui, P 2024, ‘Evolution of plant genome size and composition’, Genomics, Proteomics & Bioinformatics, vol. 22, no. 5,
Hélix-Nielsen, C 2018, ‘Biomimetic membranes as a technology platform: challenges and opportunities’, Membranes, vol. 8, no. 3,
Hotaling, S, Kelley, JL & Frandsen, PB 2021, ‘Toward a genome sequence for every animal: Where are we now?’, Proceedings of the National Academy of Sciences, vol. 118, no. 52,
Hunter, P 2008, ‘A toxic brew we cannot live without’, EMBO reports, vol. 9, pp. 15–18,
Kafri, M, Metzl-Raz, E, Jona, G & Barkai, N 2016, ‘The Cost of Protein Production’, Cell Reports, vol. 14, pp. 22–31,
Kerr-Phillips, T, Schon, B & Barker, D 2022, ‘Polymeric materials and microfabrication techniques for liquid filtration membranes’, Polymers, vol. 14, no. 19,
Kingsbury, RS, Wang, J & Coronell, O 2020, ‘Comparison of water and salt transport properties of ion exchange, reverse osmosis, and nanofiltration membranes for desalination and energy applications’, Journal of Membrane Science, vol. 604,
Krämer, U 2010, ‘Metal hyperaccumulation in plants’, Annual Review of Plant Biology, vol. 61, pp. 517–534,
Kumar, M, Grzelakowski, M, Zilles, J, Clark, M & Meier, W 2007, ‘Highly permeable polymeric membranes based on the incorporation of the functional water channel protein Aquaporin Z’, Proceedings of the National Academy of Sciences, vol. 104, no. 52,
Lair, L, Ouimet, JA, Dougher, M, Boudouris, BW, Dowling, AW & Phillip, WA 2024, ‘Critical mineral separations: opportunities for membrane materials and processes to advance sustainable economies and secure supplies’, Annual Review of Chemical and Biomolecular Engineering, vol. 15, pp. 243–266,
Lane, N & Martin, WF 2012, ‘The Origin of membrane bioenergetics’, Cell, vol. 151, no. 7,
Li, X, Chou, S, Wang, R, Shi, Lei, Fang, W, Chaitra, G, ... Fane, AG 2015, ‘Nature gives the best solution for desalination: Aquaporin-based hollow fiber composite membrane with superior performance’, Journal of Membrane Science, vol. 494, pp. 68–77,
Lian, J, Ding, S, Cai, J, Zhang, D, Xu, Z & Wang, X 2009, ‘Improving aquaporin Z expression in Escherichia coli by fusion partners and subsequent condition optimisation’, Applied Microbiology and Biotechnology, vol. 82, pp. 463–470,
Lim, YJ, Goh, K & Wang, R 2022, ‘The coming of age of water channels for separation membranes: from biological to biomimetic to synthetic’, Chemical Society Reviews, vol. 11,
Lindahl, E & Sansom, MSP 2008, ‘Membrane proteins: molecular dynamics simulations’, Current Opinion in Structural Biology, vol. 18, no. 4, pp. 425–431,
Liu, G, Zhou, B, Liu, J & Zhao, H 2021, ‘The bionic water channel of ultra-short, high affinity carbon nanotubes with high water permeability and proton selectivity’, Sustainability, vol. 13, no. 1,
Lu, C, Bonini, A, Viel, JH & Maglia, G 2025, ‘Toward single-molecule protein sequencing using nanopores’, Nature Biotechnology, vol. 43, pp. 312–322,
McGaughey, SA, Iqbal, S, De Rosa, A, Caley, JA, Kaksonen, AH, Villa-Gomez, D & Byrt, CS 2025, ‘Interactions of rare earth elements with living organisms and emerging biotechnical applications’, Plants, People, Planet,
McNulty, T, Hazen, N & Park, S 2022, ‘Processing the ores of rare-earth elements’, MRS Bulletin, vol. 47, pp. 258–266,
Merchant, SS 2010, ‘The elements of plant micronutrients’, Plant Physiology, vol. 154, no. 2, pp. 512–515,
Minerals Research Institute of Western Australia (MRIWA) 2024, Alternative Use of Tailings and Waste, viewed 19 March 2025,
Mining Weekly 2024, Tailings Remining Can Meet Critical Minerals Demand, viewed 4 April 2025,
National Human Genome Research Institute 2021, The Cost of Sequencing a Human Genome, viewed 10 April 2025,
Oliva, R, Calamita, G, Thornton, JM & Pellegrini-Calace, M 2010, ‘Electrostatics of aquaporin and aquaglyceroporin channels correlates with their transport selectivity’, Proceedings of the National Academy of Sciences, vol. 107, no. 9,
Osman, A, Chen, Z, Elgarahy, A, Farghali, M, Mohamed, IMA, Priya, AK, ... Yap, PS 2024, ‘Membrane Technology for Energy Saving: Principles, Techniques, Applications, Challenges, and Prospects’, Advanced Energy & Sustainability Research, vol. 5, no. 5,
Panayotova, M & Panayotova, V 2021, ‘Application of membrane processes in mining and mineral processing’, Second International Conference on Sustainable Futures: Environmental, Technological, Social and Economic Matters, vol. 280,
Panchy, N, Lehti-Shiu, M & Shiu, SH 2016, ‘Evolution of Gene Duplication in Plants’, Plant Physiology, vol. 171, no. 4, pp. 2294–2316,
Park, HB, Kamcev, J, Robeson, LM, Elimelech, M & Freeman, BD 2017, ‘Maximizing the right stuff: The trade-off between membrane permeability and selectivity’, Science, vol. 356, no. 6343,
Patel, SK, Iddya, A, Qian, J & Elimelech, M 2025, ‘Approaching infinite selectivity in membrane-based aqueous lithium extraction via solid-state ion transport’, Science Advances, vol. 11, no. 9,
Pellicer, J, Hidalgo, O, Dodsworth, S & Leitch, IJ 2018, ‘Genome size diversity and its impact on the evolution of land plants’, Genes, vol. 9, no. 2,
Perry, M, Madsen, SU, Jørgensen, T, Braekevelt, S, Lauritzen, K & Hélix-Nielsen, C 2015, ‘Challenges in Commercializing biomimetic membranes’, Membranes, vol. 5, no. 4, pp. 685–701,
Quirk, RP, Kinning, DJ & Fetters, LJ 1996, ‘1 - block copolymers’, in G Allen & JC Bevington (eds), Comprehensive Polymer Science and Supplements, Pergamon, Oxford, pp. 1–26.
Reeves, RD, Baker, AJM, Jaffré, T, Erksine, PD, Echevarria, G & van der Ent, A 2017, ‘A global database for plants that hyperaccumulate metal and metalloid trace elements’, New Phytologist, vol. 218, no. 2, pp. 407–411,
Ren, Q, Chen, K & Paulsen, IT 2006, ‘TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels’, Nucleic Acids Research, vol. 28, no. 35,
Rocha, RA, Alexandrov, K & Scott, C 2024, ‘Rare earth elements in biology: From biochemical curiosity to solutions for extractive industries’, Microbial Biotechnology, vol. 17, no. 6,
Sackville, MA, Gillis, JA & Brauner, CJ 2024, ‘The origins of gas exchange and ion regulation in fish gills: evidence from structure and function’, Journal of Comparative Physiology B, vol. 194, pp. 557–568,
Sands, JM & Layton, HE 2014, ‘Advances in understanding the urine-concentrating mechanism’, Annual Review of Physiology, vol. 76, pp. 387–409,
Scott, M & Hwa, Terence 2011, ‘Bacterial growth laws and their applications’, Current Opinion in Biotechnology, vol. 22, no. 4, pp. 559–565,
Senovilla, M, Castro-Rodríguez, R, Abreu, I, Escudero, V, Kryvoruchko, I, Udvardi, MK, ... González-Guerrero, M 2018, ‘Medicago truncatula copper transporter 1 (MtCOPT1) delivers copper for symbiotic nitrogen fixation’, New Phytologist, vol. 218, no. 2, pp. 696–709,
Shen, YX, Saboe, PO, Sines, IT, Erbakan, M & Kumar, M 2014, ‘Biomimetic membranes: A review’, Journal of Membrane Science, vol. 454, pp. 359–381,
Shirvani, T 2024, ‘The role of bioengineering in building a bioeconomy’, Nature Reviews Bioengineering, vol. 2, pp. 908–910,
Smart Water Magazine 2023, Aquaporin and Singapore’s PUB work on biomimetic low-energy RO membrane demonstration, viewed 10 April 2025,
Sterck, L, Rombauts, S, Vandepoele, K, Rouzé, P & Van de Peer, Y 2007, ‘How many genes are there in plants (… and why are they there)?’, Current Opinion in Plant Biology, vol. 10, no. 2, pp. 199–203,
Sterlitech 2017, Aquaporin Hollow Fiber FO Membrane Modules (AQPHFFO2), viewed 4 April 2025,
Sterlitech 2019, Introducing the Aquaporin Inside HFFO14 Hollow Fiber FO Membrane Module, viewed 4 April 2025,
Tang, C & Bruening, ML 2020, ‘Ion separations with membranes’, Journal of Polymer Science, vol. 58, no. 20, pp. 2831–2856,
Tomala, K & Korona, R 2013, ‘Evaluating the Fitness Cost of Protein Expression in Saccharomyces cerevisiae’, Genome, Biology and Evolution, vol. 14, no. 5, pp. 2051–2060,
Tripathi, NK & Shrivastava, A 2019, ‘Recent Developments in Bioprocessing of Recombinant Proteins: Expression Hosts and Process Development’, Frontiers in Bioengineering and Biotechnology, vol. 7,
Tyerman, SD, McGaughey, SA, Qiu, J, Yool, AJ & Byrt, CS 2021, ‘Adaptable and Multifunctional Ion-Conducting Aquaporins’, Annual Review of Plant Biology, vol. 17, no. 72, pp. 703–736,
Wagh, P, Zhang, X, Blood, R, Kekenes-Huskey, PM, Rajapaksha, P, Wei, Y & Escobar, IC 2019, ‘Increasing Salt Rejection of Polybenzimidazole Nanofiltration Membranes via the Addition of Immobilized and Aligned Aquaporins’, Processes, vol. 7, no. 2,
Wang, C, Du, X, Gao, F, Hao, X & Guan, G 2024b, ‘Electrochemically switched ion separation technologies: A review on electroactive ion exchange materials and system architectures’, Chemical Engineering Journal, vol. 490,
j.cej.2024.151708
Wang, H, Chen, Z, Feng, L, Chen, Z, Owens, G & Chen, Z 2024a, ‘Uptake and transport mechanisms of rare earth hyperaccumulators: A review’, vol. 351,
Wang, R & Lin, S 2024, ‘Membrane Design Principles for Ion-Selective Electrodialysis: An Analysis for Li/Mg Separation’, Environmental Science & Technology, vol. 58, no. 7,
Werner, TT, Bach, PM, Yellishetty, M, Amirpoorsaeed, F, Walsh, S, Miller, A, ... Wu, X 2020, ‘A geospatial database for effective mine rehabilitation in Australia’, Minerals, vol. 10, no. 9,
Wesseler, J & Zhu, M 2024, ‘The contribution of the bioeconomy to sustainable development’, Engineering, vol. 43, no. 12,
pp. 25–27,
Widmer, J & Norgrove, L 2023, ‘Identifying candidates for the phytoremediation of copper in viticultural soils: A systematic review’, Environmental Research, vol. 216,
Yuan, M, Liu, C, Liu, WS, Guo, MN, Morel, JL, Huot, H, ... Qiu, RL 2018, ‘Accumulation and fractionation of rare earth elements (REEs) in the naturally grown Phytolacca americana L. in southern China’, International Journal of Phytoremediation, vol. 20, no. 5, pp. 415–423,
Zhang, Y, Almodovar-Arbelo, NE, Weidman, JL, Corti, DS, Boudouris, BW & Phillip, WA 2018, ‘Fit-for-purpose block polymer membranes molecularly engineered for water treatment’, npj Clean Water, vol. 1,
Zhao, Y, Qiu, C, Li, X, Vararattanavech, A, Shen, W, Torres, J, ... Tang, CY 2012, ‘Synthesis of robust and high-performance aquaporin-based biomimetic membranes by interfacial polymerisation-membrane preparation and RO performance characterisation’, Journal of Membrane Science, vol. 423, pp. 422–428,
Zhao, Y, Wang, H, Li, Y, Wang, M & Xiang, X 2020, ‘An integrated membrane process for preparation of lithium hydroxide from high Mg/Li ratio salt lake brine’, Desalination, vol. 493,
Zheng, HX, Liu, WS, Sun, D, Zhu, SC, Li, Y, Yang, YL, ... Tang, YT 2023, ‘Plasma-membrane-localized transporter NREET1 is responsible for rare earth element uptake in hyperaccumulator Dicranopteris linearis’, Environmental Science & Technology, vol. 57, no. 17, pp. 6922–6933,




© Copyright 2025, Australian Centre for Geomechanics (ACG), The University of Western Australia. All rights reserved.
View copyright/legal information
Please direct any queries or error reports to repository-acg@uwa.edu.au